Following a heartbreaking loss to Atletico Madrid on matchday one, RB Leipzig will aim to secure their first Champions League victory this season when they host unbeaten Juventus on Wednesday. The Bundesliga outfit suffered a late setback in Madrid, while Juventus made a triumphant return to the competition, defeating Dutch champions PSV Eindhoven.

RB Leipzig’s challenging league-phase fixtures began with a tough trip to Atletico Madrid’s Metropolitano, where they sought at least a point. However, despite Benjamin Sesko’s early goal, they conceded a late winner (2-1). Leipzig’s difficult group stage draw includes matches against Juventus, Inter Milan, Liverpool, Sporting Lisbon, and Aston Villa. The 2-1 loss remains Leipzig’s only setback in 19 games across all competitions. They’ve since rebounded with four points from two Bundesliga matches, including a 4-0 thrashing of Augsburg last weekend, maintaining their club-record unbeaten run.Sesko’s early brace against Augsburg boosted morale ahead of Leipzig’s Champions League clash with Italian opposition, Juventus. Juventus made a triumphant return to the Champions League under Thiago Motta, defeating PSV 3-1. The victory highlighted a new era, with 19-year-old Kenan Yildiz scoring a stunning opener and becoming Juve’s youngest Champions League scorer. Unbeaten in seven games, Juventus broke their Serie A goal drought with a 3-0 win over Genoa, featuring Dusan Vlahovic’s second-half brace. Despite struggles from big-money signings, Juve aims to overcome a dismal away record in the Champions League, having lost four of their last five and three consecutive away matches – their longest such streak in a decade.

Motta seeks to become the third Juventus manager to secure consecutive wins in his first two UEFA Champions League matches, emulating legendary predecessors. A victory over RB Leipzig would halt Juventus’s four-game losing streak in away Champions League matches and cement Motta’s promising start. Leipzig’s Marco Rose may rotate his lineup, with Antonio Nusa facing competition from Christoph Baumgartner and Arthur Vermeeren for a starting spot alongside Lois Openda and Benjamin Sesko.Dusan Vlahovic is poised to lead Juventus’s attack against Leipzig, supported by Teun Koopmeiners, Nico Gonzalez, and Kenan Yildiz. Michele Di Gregorio will likely replace Mattia Perin in goal. Leipzig’s stingy defence, having conceded just two Bundesliga goals, will face a Juventus side that has shipped only one goal this season. The tightly contested match may hinge on a single moment of brilliance.

With both teams boasting impressive defensive records, the match may hinge on a single moment of brilliance or a strategic mistake. Leipzig’s attacking flair, combined with their home advantage, might give them the edge needed to secure a crucial victory.

Best Tip: Leipzig win or draw

Correct score: 2-1